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Calcium
Supplements Protect Against Colorectal Cancer
Calcium
supplements moderately reduce the risk of recurring polyp
growth in the colon and appear to reduce the risk of colon
cancer, according to a new national study. Most physicians
already believe calcium supplements delay the age-related,
bone-thinning condition known as osteoporosis.
The
study involved a four-year follow-up of 832 patients who
had polyps removed. Doctors consider polyps in the colon,
also called colorectal adenomas, a strong precursor to cancer.
Researchers
found 31 percent of 409 patients randomly selected to receive
1200 milligrams of calcium carbonate daily developed one
or more polyps during the study. Thirty-eight percent of
423 volunteers who received an inactive compound, or placebo,
showed new polyp growth.
"In
the treatment group, we found overall a 24 percent decrease
in the number of polyps and a 19 percent decrease in the
risk of recurrence," said Dr. Robert Sandler, professor
of medicine at the University of North Carolina at Chapel
Hill School of Medicine. "This represents a significant,
although moderate, reduction in the risk of recurrent colon
adenomas."
A
chief researcher in the study and co-director of UNC-CH’s
Center for Gastrointestinal Biology and Disease, Sandler
praised calcium supplements as safe and probably effective
in preventing colon cancer and slowing osteoporosis.
"People
who have had adenomas in the past still need to have regular
colon examinations by their physicians," he said. "We need
more research on preventing colon cancer because this work
is not the final answer."
Patients
were treated at six clinical centers at the Cleveland Clinic
Foundation, the Dartmouth-Hitchcock Medical Center, and
the universities of Iowa, Southern California, Minnesota
and North Carolina. Dr. John Baron of Dartmouth-Hitchcock
was overall study director.
"Colon cancer is a big problem in the United States," Sandler
said. "It is the second leading cause of cancer deaths.
This year we expect 67,000 new cases in women and 65,000
new cases in men."
Physicians
believe 90 percent or more of colon cancers evolve from
polyps, he said. Earlier animal research and observational
studies in humans suggested that calcium might lower the
risk of colon polyps and cancer. The new study did not directly
address the questions of whether calcium supplements affect
polyps changing to invasive cancer but is still good news.
Diets
rich in vegetables and fruits also have been associated
with lower risks, while diets high in animal fat and red
meat seem to boost the chance of cancer.
Patients,
three-quarter of whom were men, averaged just over age 60.
The National Institutes of Health supported the new study.
Go to main page of
A to B CALM
Read the Calcium
FAQ
Question? Email us!
"These
statements have not been evaluated by the FDA.
This product is not intended to diagnose, cure, prevent or treat
any diseases."
The above is a Government ORDERED statement.
It is NOT based in either reality or sanity.
Just like our Government.
In
a landmark decision on Friday, Jan. 15, 1999, the US Court of Appeals
for the District of Columbia ruled that
the health claim rules imposed by the FDA unconstitutional
and in violation of the Administrative Procedure Act.
The court instructed the FDA to allow the use of disclaimers on
labels rather than to suppress these claims outright.
The court further held prohibiting nutrient disease relationship
claims invalid under the first Amendment to the Constitution.
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